Infusion Nurses Society · 9th Edition 2024

Infusion Nurses Society (INS) 2024 Standards of Practice Crosswalk

A clinical synthesis of the 9th edition (2024) Infusion Therapy Standards of Practice, analyzing vascular access device selection algorithms, ultrasound guidance, and flushing standards.

Clinical Peer Review: Sarah Jenkins, MSN, RN, CRNI, VA-BC Published: October 2026 Verified Board Member →

1. Vascular Access Device (VAD) Selection Algorithm

The 9th Edition of the INS Standards of Practice (published in January/February 2024) updates the clinical decision tree for selecting the appropriate vascular access device (VAD):

  • Peripheral Intravenous Catheters (PIVC) & Midlines: Indicated when anticipated intravenous therapy duration is less than 14 days, the prescribed infusate is non-vesicant, solution osmolarity is <900 mOsm/L, and pH is maintained between 5 and 9.
  • Central Vascular Access Devices (CVAD: PICC, Tunneled CVC, Implanted Port): Mandatory when therapy duration exceeds 14 days, for continuous vesicant administration, parenteral nutrition with osmolarity >900 mOsm/L, solutions with extreme pH (<5 or >9), or when high-flow volume resuscitation is required.

2. Catheter-to-Vein Ratio Standard (<=45% Vein Diameter)

One of the most impactful clinical safety updates in the 2024 INS Standards mandates that the external diameter of a vascular catheter must occupy no more than 45% of the internal vein lumen diameter measured under ultrasound guidance:

TABLE 1: INS 2024 CORE CLINICAL PRACTICE RECOMMENDATIONS
Journal of Infusion Nursing · 9th Edition Standards
Clinical Practice Domain INS 2024 Standard Recommendation Evidence Rating Safety & Regulatory Impact
Catheter-to-Vein Ratio Catheter occupies <=45% of internal vein diameter assessed under ultrasound Level I (A) Reduces deep vein thrombosis (DVT) by up to 70%
PIVC Dwell Time Clinically indicated removal (routine 72–96h replacement abandoned) Level I (A) Reduces unnecessary venipunctures, pain, and hospital costs
DIVA Patients Ultrasound guidance mandatory for difficult vascular access Level I (A) Increases first-pass cannulation success from 35% to >85%
Flushing & Locking Push-pause pulsatile flush; preservative-free 0.9% Normal Saline Level I (B) Eliminates intraluminal fibrin buildup and line occlusions
Skin Antisepsis Alcoholic chlorhexidine (>0.5% CHG in 70% IPA) with verified air dry Level I (A) Gold standard for vascular access skin prep

3. Difficult Vascular Access (DIVA) & Ultrasound Guidance

Blind venipuncture attempts in patients with Difficult Vascular Access (DIVA) result in vessel trauma, nerve damage, arterial puncture, and hematomas. The 2024 Standards dictate that clinicians must assess vascular anatomy with real-time ultrasound before cannulation, limiting blind attempts to a maximum of two per clinician (and four total per patient before escalation to vascular access specialists).

Evidence Base & Literature Citations

  1. Infusion Nurses Society. Infusion Therapy Standards of Practice, 9th Edition. J Infus Nurs. 2024;47(1S):S1-S228. DOI: 10.1097/NAN.0000000000000532
  2. Nickel B, et al. Infusion Therapy Standards of Practice: An Overview of the 2024 Ninth Edition. J Infus Nurs. 2024;47(1):12-18. DOI: 10.1097/NAN.0000000000000536

Clinical Practice Boundary Notice

This protocol provides evidence-based guidance reflecting INS 2024 Standards of Practice and CDC recommendations. Clinical judgment, institutional policy, and patient-specific variables must guide individualized bedside care.